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Placebo Effect a Major Driver of Pain Reduction in Cannabis Trials

A strong placebo response may be largely responsible for the significant pain reduction observed in clinical trials of cannabis-based therapies, results of a new meta-analysis suggest. Investigators found that while the effect size of cannabinoids on pain intensity was significant, the placebo effect was about the same. “The data from the present meta-analysis, including 1459

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Trends in Cannabis Use Disorder Diagnoses in the U.S. Veterans Health Administration, 2005–2019

Since 2005, diagnoses of cannabis use disorder have increased substantially among VHA patients, as they have in the general population and other patient populations. Possible explanations warranting investigation include decreasing perception of risk, changing laws, increasing cannabis potency, stressors related to growing socioeconomic inequality, and use of cannabis to self-treat pain. Clinicians and the public

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Cannabinoid hyperemesis syndrome in North America: evaluation of health burden and treatment prevalence

Survey data suggest patients with CHS almost universally suffer from a cannabis use disorder, which has significant treatment implications. Treatment prevalence in the ED has increased substantially over a very short time period, with the highest rates seen during the Covid-19 pandemic. For more information on the International Academy on the Science and Impact of

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Legalizing psychedelics does more harm than good

Citizens of Colorado will be voting on Proposition 122, which would allow decriminalization, distribution and access to psychedelics. It will also allow possession, personal use and growing, as well as uncompensated gifting. Is this going to be good for Colorado and personal health? There is emerging data that components of psychedelics may have medicinal value

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Marijuana-dependent patients may face higher infection rates following knee and shoulder arthroscopy

Patients who are dependent on marijuana may face higher infection rates following knee and shoulder arthroscopy-;a minimally invasive surgery in which a small camera is inserted to diagnose and sometimes treat injury-;according to a study presented at the Scientific Forum of the American College of Surgeons (ACS) Clinical Congress 2022. Using PearlDiver, a national insurance

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OSHA: Cultivation facility worker died after inhaling ground cannabis dust

A marijuana cultivation facility worker who died in January could not breathe after inhaling ground cannabis dust at the Holyoke site, an Occupational Safety and Health Administration investigation found. While filling pre-rolls at the Trulieve facility on Jan. 7, 27-year-old Lorna McMurrey said she couldn’t breathe, according to OSHA’s investigation summary, and later died at

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Testing the cannabis gateway hypothesis in a national sample of Spanish adolescents

Please cite this article as: A. García-Pérez, G. Aonso-Diego, S. Weidberg, R. Secades-Villa, Testing the cannabisgateway hypothesis in a national sample of Spanish adolescents, Addictive Behaviors Addictive Behaviors (2023),doi: https://doi.org/10.1016/j.addbeh.2023.107751 This article has undergone enhancements after acceptance, such as the addition of a coverpage and metadata, and formatting for readability, but it is not yet

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Legalizing Marijuana Is a Big Mistake

Of all the ways to win a culture war, the smoothest is to just make the other side seem hopelessly uncool. So it’s been with the march of marijuana legalization: There have been moral arguments about the excesses of the drug war and medical arguments about the potential benefits of pot, but the vibe of

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