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The implementation and public health impacts of cannabis legalization in Canada: a systematic review

Abstract Aims We provide a narrative summary of research on changes in cannabis arrests, cannabis products, and prices, cannabis use, and cannabis-related harm since legalization. Methods We systematically searched for research on the impacts of cannabis legalization in Canada in PubMed, Embase, Statistics Canada, government websites, and Google Scholar, published between 2006 and 2021. Results

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Placebo Effect a Major Driver of Pain Reduction in Cannabis Trials

A strong placebo response may be largely responsible for the significant pain reduction observed in clinical trials of cannabis-based therapies, results of a new meta-analysis suggest. Investigators found that while the effect size of cannabinoids on pain intensity was significant, the placebo effect was about the same. “The data from the present meta-analysis, including 1459

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Trends in Cannabis Use Disorder Diagnoses in the U.S. Veterans Health Administration, 2005–2019

Since 2005, diagnoses of cannabis use disorder have increased substantially among VHA patients, as they have in the general population and other patient populations. Possible explanations warranting investigation include decreasing perception of risk, changing laws, increasing cannabis potency, stressors related to growing socioeconomic inequality, and use of cannabis to self-treat pain. Clinicians and the public

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Cannabinoid hyperemesis syndrome in North America: evaluation of health burden and treatment prevalence

Survey data suggest patients with CHS almost universally suffer from a cannabis use disorder, which has significant treatment implications. Treatment prevalence in the ED has increased substantially over a very short time period, with the highest rates seen during the Covid-19 pandemic. For more information on the International Academy on the Science and Impact of

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Legalizing psychedelics does more harm than good

Citizens of Colorado will be voting on Proposition 122, which would allow decriminalization, distribution and access to psychedelics. It will also allow possession, personal use and growing, as well as uncompensated gifting. Is this going to be good for Colorado and personal health? There is emerging data that components of psychedelics may have medicinal value

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Marijuana-dependent patients may face higher infection rates following knee and shoulder arthroscopy

Patients who are dependent on marijuana may face higher infection rates following knee and shoulder arthroscopy-;a minimally invasive surgery in which a small camera is inserted to diagnose and sometimes treat injury-;according to a study presented at the Scientific Forum of the American College of Surgeons (ACS) Clinical Congress 2022. Using PearlDiver, a national insurance

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Libby Stuyt Interview on Randy Tobler show

Exciting News! Libby Stuyt’s Interview on Randy Tobler Show! Hey everyone, we wanted to share some thrilling news! The brilliant Dr. Libby Stuyt recently had an enlightening interview on Randy Tobler Show. Dr. Stuyt is known for her groundbreaking work in the field of addiction medicine and mental health. Her insights are nothing short of

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Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

Introduction Cannabis contains over 100 cannabinoids, of which Δ9-tetrahydrocannabinol and cannabidiol are the most clinically relevant. Tetrahydrocannabinol is a partial agonist at CB1 and binds CB2 receptors. CB1 is widely expressed by central and peripheral neurones but also by immune cells and other type of cells in the brain and in the periphery, and when

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IASIC Speaker Series Presents: Case Report on Cannabis-Induced Acute Encephalopathy in Elderly After Taking CBD

The International Academy on the Science and Impact of Cannabis (IASIC) is excited to present the IASIC Speaker Series. Presented free of charge, this ongoing educational seminar series will focus on the science, data and peer-reviewed research surrounding marijuana and will be led by international medical experts. This non-partisan and non-political series is continually developed,

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