Cannabinoids in Medicine: Limitless Hope or Hype?

Regardless of the type of substance-dependent addiction — whether alcohol, opiates, nicotine, or cannabinoids — the brain pathway is the same: the dopamine system. This system is also responsible for curiosity, desire, learning, and actions. Various substances lead to increased neurotransmitter release.

The endocannabinoid system acts as a damper on this system. System stabilization is inhibited by the high-affinity binding of delta (9)-trans-tetrahydrocannabinol (THC) to CB1 receptors. The psychotropic component of cannabis naturally accounts for 1%–2% of the active substance. However, this proportion has now increased to 10%­–20% as a result of selective breeding. At the same time, the proportion of cannabidiol (CBD), the nonpsychoactive counterpart, has fallen.

To read the full article in Medscape, click here: https://www.medscape.com/viewarticle/973874?src=soc_tw_share

For more information on the International Academy on the Science and Impact of Cannabis, and to join, please visit www.IASIC1.org.

Visit the IASIC Library here (https://iasic1.org/library/). The IASIC Library is intended as a user-friendly reference of the published medical literature.

Like this article?

Share on Facebook
Share on Twitter
Share on Linkdin
Share on Pinterest

Related Posts

Libby Stuyt Interview on Randy Tobler show

Exciting News! Libby Stuyt’s Interview on Randy Tobler Show! Hey everyone, we wanted to share some thrilling news! The brilliant Dr. Libby Stuyt recently had an enlightening interview on Randy Tobler Show. Dr. Stuyt is known for her groundbreaking work in the field of addiction medicine and mental health. Her insights are nothing short of

Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

Introduction Cannabis contains over 100 cannabinoids, of which Δ9-tetrahydrocannabinol and cannabidiol are the most clinically relevant. Tetrahydrocannabinol is a partial agonist at CB1 and binds CB2 receptors. CB1 is widely expressed by central and peripheral neurones but also by immune cells and other type of cells in the brain and in the periphery, and when

Medical marijuana access and prolonged opioid use among adolescents and young adults

Abstract Background and Objectives Laws liberalizing access to medical marijuana are associated with reduced opioid analgesic use among adults, but little is known about the impact of such policies on adolescents and young adults. Methods This retrospective cohort study used 2005 to 2014 claims from MarketScan® Commercial database, which covers all 50 states and Washington

Scroll to Top