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Cannabinoid hyperemesis syndrome in North America: evaluation of health burden and treatment prevalence

December 30, 2022 No Comments

Survey data suggest patients with CHS almost universally suffer from a cannabis use disorder, which has significant treatment implications. Treatment prevalence in the ED has increased substantially over a very short time period, with the highest rates seen during the Covid-19 pandemic. For more information on the International Academy on the Science and Impact of

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Comorbidity and Coaggregation of Major Depressive Disorder and Bipolar Disorder and Cannabis Use Disorder in a Controlled Family Study

November 7, 2022 No Comments

In this cross-sectional study of 586 probands and 698 first-degree relatives, cannabis use disorder and bipolar disorder II in probands were associated with an independent increase in risk of cannabis use disorder in relatives; bipolar disorder I and major depressive disorder in probands were not significantly associated with cannabis use disorder in relatives. The risk

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Clinical management of cannabis withdrawal

August 2, 2022 No Comments

Cannabis withdrawal is a well-characterized phenomenon that occurs in approximately half of regular and dependent cannabis users after abrupt cessation or significant reductions in cannabis products that contain Δ9-tetrahydrocannabinol (THC). This review describes the diagnosis, prevalence, course and management of cannabis withdrawal and highlights opportunities for future clinical research. Read the full study published in

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Highly potent weed creating marijuana addicts worldwide, study says

July 29, 2022 No Comments

Higher concentrations of tetrahydrocannabinol or THC — the part of the marijuana plant that makes you high — are causing more people to become addicted in many parts of the world, a new review of studies found. Read the full article from CNN here: https://amp.cnn.com/cnn/2022/07/25/health/marijuana-potency-addiction-study-wellness/index.html For more information on the International Academy on the Science

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Cannabinoids in Medicine: Limitless Hope or Hype?

July 15, 2022 No Comments

Regardless of the type of substance-dependent addiction — whether alcohol, opiates, nicotine, or cannabinoids — the brain pathway is the same: the dopamine system. This system is also responsible for curiosity, desire, learning, and actions. Various substances lead to increased neurotransmitter release. The endocannabinoid system acts as a damper on this system. System stabilization is

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Notice of Retraction and Replacement

July 13, 2022 No Comments

To the Editor On behalf of our coauthors, we write to respond to concerns raised about the methods and analyses for the Research Letter, “Association of Marijuana Legalization With Marijuana Use Among US High School Students, 1993-2019,” published in JAMA Network Open on September 7, 2021.1 These concerns were brought to our attention by readers

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First Medical Textbook on Cannabis in Medicine

Listen to podcast High Truths on Drugs and Addiction on your favorite platform. ​Hightruth.com

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Libby Stuyt Interview on Randy Tobler show

Exciting News! Libby Stuyt’s Interview on Randy Tobler Show! Hey everyone, we wanted to share some thrilling news! The brilliant Dr. Libby Stuyt recently had an enlightening interview on Randy Tobler Show. Dr. Stuyt is known for her groundbreaking work in the field of addiction medicine and mental health. Her insights are nothing short of

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Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

Introduction Cannabis contains over 100 cannabinoids, of which Δ9-tetrahydrocannabinol and cannabidiol are the most clinically relevant. Tetrahydrocannabinol is a partial agonist at CB1 and binds CB2 receptors. CB1 is widely expressed by central and peripheral neurones but also by immune cells and other type of cells in the brain and in the periphery, and when

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IASIC Speaker Series Presents: Case Report on Cannabis-Induced Acute Encephalopathy in Elderly After Taking CBD

The International Academy on the Science and Impact of Cannabis (IASIC) is excited to present the IASIC Speaker Series. Presented free of charge, this ongoing educational seminar series will focus on the science, data and peer-reviewed research surrounding marijuana and will be led by international medical experts. This non-partisan and non-political series is continually developed,

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