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Marijuana Use Increased in Pregnant Women with HIV

In this cohort study including 2310 pregnant and postpartum individuals living with HIV from the Surveillance Monitoring for Antiretroviral Toxicities (SMARTT) study, use of marijuana increased from 2007 to 2019 and was more frequent in locations with medical marijuana legalization. The prevalence of alcohol and opioid use did not change over that time. To read

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Cannabis Use in Pregnancy May Lead to a More Anxious, Aggressive Child

Children of women who use marijuana during or soon after pregnancy are twice as likely as other kids to become anxious, aggressive or hyperactive, according to a new study (https://www.pnas.org/content/118/47/e2106115118). The findings add weight to a growing body of evidence linking cannabis use during pregnancy to psychiatric problems in children. The study does not, however,

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Epidemiological overview of multidimensional chromosomal and genome toxicity of cannabis exposure in congenital anomalies and cancer development

Abstract: Cannabis and cannabinoids are implicated in multiple genotoxic, epigenotoxic and chromosomal-toxic mechanisms and interact with several morphogenic pathways, likely underpinning previous reports of links between cannabis and congenital anomalies and heritable tumours. However the effects of cannabinoid genotoxicity have not been assessed on whole populations and formal consideration of effects as a broadly acting

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UCSD Study: Docs Should Screen For Cannabis Use Disorder in Pregnant Women

Women diagnosed with cannabis use disorder had babies who were more likely to be born preterm, have a low birth weight and be small for their gestational age — all factors that can require greater or more intense medical care or presage later health issues. https://www.nbcsandiego.com/news/local/ucsd-study-docs-should-screen-for-cannabis-use-disorder-in-pregnant-women/2584996/

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Cannabis can alter male sperm DNA changes associated with autism

Parental cannabis use has been associated with adverse neurodevelopmental outcomes in offspring, but how such phenotypes are transmitted is largely unknown. Using reduced representation bisulphite sequencing (RRBS), we recently demonstrated that cannabis use is associated with widespread DNA methylation changes in human and rat sperm. Discs-Large Associated Protein 2 (DLGAP2), involved in synapse organization, neuronal

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Major Uptick Reported in Cannabis Vaping for All Adolescents

Cannabis vaping is increasing as the most popular method of cannabis delivery among all adolescents in the U.S., as is the frequency of cannabis vaping, according to research at Columbia University Mailman School of Public Health. The study found that the frequency of vaping cannabis among adolescents from all demographic groups is reported at six

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The phytochemical diversity of commercial Cannabis in the United States

The legal status of Cannabis is changing, fueling an increasing diversity of Cannabis-derived products. Because Cannabis contains dozens of chemical compounds with potential psychoactive or medicinal effects, understanding this phytochemical diversity is crucial. The legal Cannabis industry heavily markets products to consumers based on widely used labeling systems purported to predict the effects of different

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What is THCP?

THCP, which is short for tetrahydrocannabiphorol and scientifically known as (-)-Trans-Δ9-tetrahydrocannabiphorol, is a natural cannabinoid and analog of THC present in varieties of cannabis. It’s thought to be 33 times more active at cannabinoid 1 (CB1) receptors than THC, causing an intense and intoxicating euphoric high. THCP’s legality is stuck between conflicting federal legislation. It’s not

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