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Effect of Medical Marijuana Card Ownership on Pain, Insomnia, and Affective Disorder Symptoms in Adults

Key Points Question  What are the risks and benefits of obtaining a medical marijuana card for adults who seek medical marijuana for pain, insomnia, and anxiety or depressive symptoms? Findings  In this randomized clinical trial involving 186 participants, immediate acquisition of a medical marijuana card increased the incidence and severity of cannabis use disorder (CUD) and resulted

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Cannabis Contaminants Limit Pharmacological Use of Cannabidiol

For nearly a century, Cannabis has been stigmatized and criminalized across the globe, but in recent years, there has been a growing interest in Cannabis due to the therapeutic potential of phytocannabinoids. With this emerging interest in Cannabis, concerns have arisen about the possible contaminations of hemp with pesticides, heavy metals, microbial pathogens, and carcinogenic compounds during the cultivation, manufacturing,

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Varied Presentations of Pediatric Patients With Positive Cannabinoid Tests

Cannabis (marijuana) is one of the most abused drugs worldwide. The past decade has seen an increase in the legalization of cannabis for both medicinal and recreational use. As of June 2021, 36 states allow the use of cannabis for medicinal purposes, and that number is expected to increase with additional states considering legalization in

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Longitudinal Course of Mental Health Symptoms Among Veterans With and Without Cannabis Use Disorder

Cannabis use disorder (CUD) is the most common non-alcohol related substance use disorder (SUD) in the United States and is especially prevalent among returning veterans. The long-term mental health correlates of CUD remain unknown, which is significant given the rise in legalization and also recreational and medicinal cannabis use nationally. In the first long-term and

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Lifetime marijuana use and epigenetic age acceleration: A 17-year prospective examination

This study was designed to assess links between lifetime levels of marijuana use and accelerated epigenetic aging. This was a prospective longitudinal study, following participants annually from age 13 to age 30. The participants were 154 individuals from a small city in the Southeastern United States. Participants completed annual assessments of marijuana use from age 13 to age

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Marijuana Legalization and Opioid Deaths

Over the last two decades there has been considerable movement at the state-level to legalize marijuana, initially for medical purposes and more recently for recreational consumption. Despite prior research, it is unclear how, if at all, these policies are related to rates of opioid-involved overdose deaths, which have trended rapidly upwards over time and represent

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Mom Says Her Son’s Delta 8 Use Turned Fatal

Meet Rita, a mom who says her son Brian’s Delta 8 usage turned fatal. Rita shares he started complaining about loss of time, blacking out and hearing voices, but she did not realize those symptoms were related to his use of Delta 8. After he took his life, a toxicology report only found THC in his

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Major Uptick Reported in Cannabis Vaping for All Adolescents

Cannabis vaping is increasing as the most popular method of cannabis delivery among all adolescents in the U.S., as is the frequency of cannabis vaping, according to research at Columbia University Mailman School of Public Health. The study found that the frequency of vaping cannabis among adolescents from all demographic groups is reported at six

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The phytochemical diversity of commercial Cannabis in the United States

The legal status of Cannabis is changing, fueling an increasing diversity of Cannabis-derived products. Because Cannabis contains dozens of chemical compounds with potential psychoactive or medicinal effects, understanding this phytochemical diversity is crucial. The legal Cannabis industry heavily markets products to consumers based on widely used labeling systems purported to predict the effects of different

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What is THCP?

THCP, which is short for tetrahydrocannabiphorol and scientifically known as (-)-Trans-Δ9-tetrahydrocannabiphorol, is a natural cannabinoid and analog of THC present in varieties of cannabis. It’s thought to be 33 times more active at cannabinoid 1 (CB1) receptors than THC, causing an intense and intoxicating euphoric high. THCP’s legality is stuck between conflicting federal legislation. It’s not

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