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Cannabinoid Content and Label Accuracy of Hemp-Derived Topical Products Available Online and at National Retail Stores

Products containing cannabinoids such as cannabidiol (CBD) have proliferated since 2018, when the Agriculture Improvement Act removed hemp (ie, cannabis containing <0.3% Δ9-tetrahydrocannabinol [THC]) from the US controlled substances list. Topical cannabinoid products can be purchased nationwide at retail stores and over the internet, yet research on these products is scarce. The objective of this

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Cannabis-Derived Oromucosal Spray Misses in MS Spasticity Trial

Topline results were announced from a phase 3 trial evaluating the efficacy and safety of nabiximols oromucosal spray (JZP378) on clinical measures of spasticity in adults with multiple sclerosis. Nabiximols oromucosal spray is an investigational complex botanical mixture formulated from extracts of the cannabis sativa plant. The investigational treatment contains the cannabinoids delta-9-tetrahydrocannabinol (THC) and

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Should the UK legalize marijuana?

After Sadiq Khan’s visit to a California cannabis farm, discussions of legalising the herb here in the UK has been brought back into the spot light. But is Mr. Khan’s glowing review of the US marijuana industry all it’s cracked up to be? The Medical Minefield speak with Michelle Leopold, whose campaigning for safer drug

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How California’s legal cannabis dream became a public health nightmare

A ROW of luxury ‘healing’ creams is guarded by a locked glass cabinet, gilded in gold trim. The packaging is stylishly minimal – clean and white with small black typeface – and beside the tubs sit decorative, artificial fruit and images of sprawling fields, with a small flyer to remind customers of the high-quality, organic

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Federal Regulations of Cannabis for Public Health in the United States

Millions of Americans use cannabis in moderation each month without any problems. However, evidence is mounting of harmful physical and mental health effects associated with heavy or long-term regular cannabis use. At the same time, existing legal markets in the United States are making high-potency cannabis products available to adult consumers. Recent international recommendations suggest

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Vaping May Open the Door to Cannabis Use in Teens

Adolescents who used e-cigarettes were significantly more likely to become new smokers of cannabis shortly thereafter, a cohort study found. Cannabis-naive adolescents reporting ever vaping at baseline were more than twice as likely to report also using cannabis when surveyed a year later (adjusted RR 2.57 vs nonusers of e-cigarettes, 95% CI 2.04-3.09), reported Ruoyan

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Clinical management of cannabis withdrawal

Cannabis withdrawal is a well-characterized phenomenon that occurs in approximately half of regular and dependent cannabis users after abrupt cessation or significant reductions in cannabis products that contain Δ9-tetrahydrocannabinol (THC). This review describes the diagnosis, prevalence, course and management of cannabis withdrawal and highlights opportunities for future clinical research. Read the full study published in

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Association of cannabis potency with mental ill health and addiction: a systematic review

Cannabis potency, defined as the concentration of Δ9-tetrahydrocannabinol (THC), has increased internationally, which could increase the risk of adverse health outcomes for cannabis users. We present, to our knowledge, the first systematic review of the association of cannabis potency with mental health and addiction (PROSPERO, CRD42021226447). We searched Embase, PsycINFO, and MEDLINE (from database inception

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WADA Executive Committee Approves 2023 Prohibited List

On September 23, the World Anti-Doping Agency’s (WADA’s) Executive Committee (ExCo) held its second meeting of the year in Sydney, Australia. ExCo members, some of whom attended in person and others virtually, were updated on WADA’s progress on key priorities, took a number of decisions – the main ones being summarized below – and made

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Doctors Inform Parents of Marijuana Use Linked to Youth Mental Health

Dr. Roneet Lev, with Scripps Hospital Emergency Room, wants to make sure parents and youth are making informed decisions and understand the risks. During Thursday’s event, doctors laid out the relationship between marijuana use and youth mental health. Lev warned that cannabis use is a suicide risk factor for people under the age of 25.

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